Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/287880940?client_source=feed&format=rss
north korea missile launch modesto st louis weather guinea bissau google stock google stock china gdp
Thursday, February 28, 2013
Video: Cardinal Wuerl: Next pope must ?keep us focused?
>> is one of the 115 cardinals who will elect the next pope. good morning. good to see you.
>> good morning. good to be with you.
>> you were in the pope's final audience this morning. some of the cardinals looked emotional, even teary. were you one of them?
>> i was. it was such a powerful moment. this is the first time ever we've had a pope in this context say good-bye. and to see the thousands and thousands of people, but also to hear him speak, what this moment means. it was a very emotional moment.
>> congregation of cardinals will start to meet perhaps late this week, early next week. have there been discussions, informal, among the cardinals about who may be the next pope?
>> most of the cardinals are just arriving now. i would suspect in the next days there will be conversation but a lot of the conversation is just getting to know better some of the other cardinals . not all the cardinals have an opportunity to come regularly to rome for meetings. so a big part of these congregations is simply getting to know your brother cardinal.
>> we just saw a piece that talked about some of the scandals and controversy the church has faced. i won't rattle them off again but do you feel finding somebody that can restore credibility to the institution is an urgent matter in electing the next pope?
>> i think the recoveryriding thing is going to be to maintain the continuity of this focus on the mission of the church , the spiritual ministry of the church . that always will involve taking care of any problems that have arisen. i think we will go into the conclave. the cardinals will go into the conclave, looking for someone who will keep us focused.
>> do you think the spiritual mission of the church , the work of the church , has been undermined by some of these scandals?
>> the church and its workings are always going to suffer when we members, the human members of the church , do not live up to the fullness of the gospel. that's part of the history of the church . when christ created the church , divine and human, failures were built into the church . the important thing is to move beyond those. right what was wrong and move into the future.
>> we've been talking about the unprecedented nature of this kind of abdication. we haven't seen it in 600 years. not totally unprecedented. do you agree with the decision? do you worry at all about the precedence that it sets?
>> going into the future, we now have a new model. it's possible for a pope simply to say -- not just intellectually, but now practically, i can't do this anymore. so i think the holy father has opened up a whole new chapter in the life of the church . but what was so beautiful about this was the way pope benedict simply said, i don't have the energy to do what i know needs to be done. and i think we all know going into the future, the work of the pope, the next pope is going to have to be the work of moving the whole church rapidly into this very modern age .
>> i have ten seconds left. if you had to choose brilliant manager, brilliant evangelist, which would you put a premium on?
>> i would always choose the evangelist, the person who can
Source: http://video.today.msnbc.msn.com/today/50970062/
lakers trade ann arbor news ides of march elizabeth smart nick young south dakota state long beach state
Friday, February 22, 2013
Governor Quinn Announces Major Capital Investment in Illinois State University - $54 Million Fine Arts Complex Will Create 775 Construction Jobs and Strengthen University?s Renowned Arts Programs
Sorry, Readability was unable to parse this page for content.
Source: http://www3.illinois.gov/PressReleases/ShowPressRelease.cfm?SubjectID=1&RecNum=10940
breitbart dead db cooper fafsa branson missouri davy jones dead monkees last train to clarksville
Rivera throws BP for first time since knee injury
New York Yankees' Mariano Rivera pitches during a workout at baseball spring training, Saturday, Feb. 16, 2013, in Tampa, Fla. (AP Photo/Matt Slocum)
New York Yankees' Mariano Rivera pitches during a workout at baseball spring training, Saturday, Feb. 16, 2013, in Tampa, Fla. (AP Photo/Matt Slocum)
New York Yankees' Mariano Rivera laughs during a workout at baseball spring training, Saturday, Feb. 16, 2013, in Tampa, Fla. (AP Photo/Matt Slocum)
TAMPA, Fla. (AP) ? Yankees closer Mariano Rivera did more than throw on Friday. He also called balls and strikes.
The 43-year old Rivera threw 25 pitches in his first batting practice session since knee surgery last year and said he was happy with the results.
"It feels great to be on the mound," said Rivera, who expects to throw BP one or two more times. "Basically, just wanted to see hitters. I'm excited. Build up, and we'll go from there."
The first batter Rivera faced was minor leaguer Rob Segedin. After the first pitch, which the right-handed batter took, Rivera said: "Strike 1." When the next pitch was taken, Rivera said: "Strike 2, you better swing."
Segedin took the advice on the third offering, and lined what would have been a single to right center.
"There you go," Rivera said.
Rivera was limited to nine games last year, his season ending when he tore the anterior cruciate ligament in his right knee while tracking down a fly ball during batting practice in Kansas City on May 3. He had surgery to repair the injury on June 12.
"He looked great," manager Joe Girardi said. "Looked like what you'd expect him to look like, which is a good thing."
Rivera is a 12-time All-Star with 608 saves in the regular season and 42 more in the postseason. After additional BP sessions, he might throw a simulated game before starting exhibition play ahead of the Yankees' April 1 opener against Boston.
Ace CC Sabathia, likely to start that opener, threw 40 pitches during his third bullpen session and intends to throw batting practice on Monday.
"Felt good. No problems," Sabathia said.
The left-hander had arthroscopic surgery Oct. 25 to remove a bone spur from his left elbow.
Shortstop Derek Jeter, coming back after ankle surgery, continues to increase his workouts. He is hitting and fielding, and participating in an indoor running program.
"Every day is more and more," Jeter said. "More agility, more running."
Andy Pettitte, who turns 41 in June, threw 24 pitches in his initial batting practice session.
Right-hander Phil Hughes, receiving treatment for bulging disk in his upper back, said he feels significantly better and could start pool work Sunday. He might resume playing catch next week.
Notes: Jorge Posada arrived in camp as a guest instructor. The former catcher again said he has no interest in making a comeback and is talking with the team about being a part-time instructor. "I'm not second guessing myself," Posada said. "I know I can't play. So, in my mind I think I made the right decision." ... RHP David Phelps is the scheduled starter for Saturday's spring training opener against Atlanta. Position players making the trip to Kissimmee include 1B Mark Teixeira, 2B Robinson Cano and SS Eduardo Nunez. ... Reliever Joba Chamberlain is scheduled to take part in a simulated game Saturday. ... Minor league pitching prospect Mark Montgomery (back spasms) threw 28 pitches in a bullpen session.
Associated Pressf 18 jet crash in virginia beach john tortorella nicki minaj beez in the trap video food network good friday f/a 18
Mike Ragogna: Bang Bang Boom Boom: Chatting with Beth Hart, The Devil Wears Prada's Mike Hranica's One & A Half Hearts, and NC Rocks OH
THE DEVIL WEARS ONE & A HALF HEARTS
Whaaaaat? The Devil Wears Prada's Mike Hranica wrote a book? And it's called One & A Half Hearts, looking back on the creation of the band's last album Dead Throne, which debuted at #10 on Billboard's Top 200? No frakin' way! (Yes, shameless Battlestar Galactica ref, and why the hell didn't Syfy commission a Blood & Chrome series from that killer pilot, but I digress...)
So here's how the website info kind of reads: "One & A Half Hearts is a subjective look at the lyrical creation of The Devil Wears Prada's fourth full length (album) Dead Throne. The band's lead vocalist analyzes the fundamentals and the importance behind the album's language. and its intentions, while constantly maintaining focus on themes of romance, idolatry, and hope." Cutting to the idolatry part right now...
A Conversation with Beth Hart
Mike Ragogna: So how are you doing, Beth Hart?
Beth Hart: Hey, how are you?
MR: Just dandy. So Bang Bang Boom Boom. Tell me everything about it. Leave nothing out.
BH: [laughs] It's such a work of love, oh my God, and there are so many love songs on it. I think it's my first record that I've actually written a lot about love. Let's see...musically, it was definitely really challenging for me. I didn't have any intention on making a record, I just had the intention about two years ago of setting off into a quest of a new kind of music for myself. It was inspired by doing a record with Joe Bonamassa. On that record, we did a lot of cover songs, and we did a bunch of jazz and blues and rock, a lot of stuff that centered around a soulful kind of thing. It inspired me so much that I thought, "Wow, I'm really going to put my head to the piano and work on some of these changes and some of these vibes, so I kind of went back and listened to a lot of stuff I was growing up listening to. I listened to a lot of genres of music--a lot of gospel, a lot of jazz, a lot of blues, a lot of hard, hard, hard rock, old school rock, a lot of modern rock, and a lot of classical music and reggae.
Those are like my forms, and so this time, I didn't really have a form of knowing what I was doing, so I pulled out all those old records again. I was listening to a lot of Joe Turner and Billie Holiday and really wanting to be fractured by like Thelonious Monk and stuff like that, all the crazy changes and fun stuff and the great lyrics. Something that I found was I was enjoying writing so much in this new genre, probably because it was fresh and something different for me. But one of the things I realized later into the writing of the record--this was before I started doing any of the co-writes, this is just stuff on my own--I noticed that my lyrics were changing from the past. The subject matters I'd choose a lot before were life and my disappointments with it and shame with myself, a lot of talking about how I felt either with myself or life in general, but not a lot about love. I noticed that that was coming up a lot in this record and it made me really happy to see how when you shift yourself musically and you start to challenge yourself musically, your stories and your philosophies on life that you didn't even know you had can show up in a lyric. I had a lot of fun with that. I'm really proud of it and I had a great time.
I wrote with some great writers, too. I wrote with James House, who's a singer, songwriter, musician. I have to give him major cred on "Caught Out In The Rain."; that was really his idea and I just love that song. I wrote with Rune Westberg on two songs, "Bang Bang Boom Boom," and "Thru The Window Of My Mind." Rune Westberg is an old friend of mine, a great songwriter, and he and I have written in the past. It was funny, I hadn't done any writing with him on this whole record, and then, right before I went in to work with Kevin Shirley who did the record for me, I just stopped by his house and we wrote two songs together really quickly and that was "Bang Bang Boom Boom" and "Thru The Window Of My Mind." I was so happy to work with him again and have such great music. I really love those two songs. I worked with Juan Winans who's an amazing songwriter and part of that whole BeBe and CeCe Winans gospel family. We wrote a great little song together called "With You Every Day."
MR: That reminds me, on this album, there's even a love song, in a way, to God. You're not being particularly reverent, but you are acknowledging your relationship cleverly through your song "Spirit Of God." I thought that was very cool.
BH: Thank you, thank you so much. You know, there's a funny story about that song. When I was a real young kid, around the age five or six, I belonged to a country club. My brother would always be looking over me and keeping an eye on me, but I'd sneak away from him and I'd go upstairs into the clubhouse. Way upstairs on the top floor is a place people would rent out for weddings or stuff like that. Usually, there wasn't anybody up there and there was always a grand piano, so I'd sneak up there and go play on the piano and have myself a good little time. One day, I'm walking up there and, mind you, I've been to Catholic church, it wasn't my favorite thing. I've always felt a love with God, but I didn't like Catholic church, it was way too serious and quiet and boring. I wasn't into it. Well, this day, I'm walking upstairs into the clubhouse and I'm hearing all this banging and booming and going crazy up there. I open the door and I look in, and there's a full-on Baptist church--choir, preacher, dancing, singing, up and down the aisles, sweating. That preacher looked over because I'd poked my head through the door and he said, "Little white girl, do you believe in the Lord?" I'm like, "I don't know?" and he's like, "Come on in and celebrate the Lord," and he put me up there with the choir and I got to sing. Everybody was so good to me, and that was one of the most amazing experiences in watching what I felt like was celebrating God the right way, where you just show all of your feeling out loud--sweat it out, dance it out... To me, that would be the right way for me to show it anyway, but it was also like seeing a great rock concert for the first time. It was unbelievable. So that's what that song is all about.
MR: Sweet. Can you take us on a little tour, maybe reveal a few more adventures of the songs that went into this album?
BH: Okay. So I turned in about forty songs to Kevin--I like to do about forty or fifty because I figure if you write a bunch of songs, there's bound to be a few in there that will work and that you'll like and whatnot. Some of the stuff I sent in was the stuff I'd been working on this last year, stuff on my own, and stuff with other songwriters who I love so much, but some of the stuff I just thought I'd throw his way was stuff I'd written four or five years ago. One of them is called "Ugliest House On The Block." Now, I really do live in the ugliest house on the block, however, I was using it more as a metaphor for the way I feel. It's like one of those hard-luck stories that you have to laugh at, because if you don't laugh at it, you're just overtaken by your own outlook on how negative it is, and we all know that no matter how bad it is, it could always be worse. So it's one of those kind of songs, to be able to laugh at the hard luck of it all and to be able to find comfort in your awareness and not ever take it so seriously. It's your life, you're alive, you've got to find gratitude in that.
MR: Yeah, nicely put.
BH: It was such a fun song to work on, and it took me a while to write that one. I didn't send it to Kevin right away; he kept asking for more and more material, and he said, "I have a feeling you're holding back some of your more personal material. Why don't you throw me some of that?" That was one of them I threw his way, and he just loved it and wanted to record it and I was very happy.
MR: Beth, let's talk about "Everything Must Change." You've actually had some major life changes especially over the last couple of years, haven't you?
BH: Yeah. It seems like my whole life has been major changes on every corner. I've always struggled with bipolar disorder but I never was medicated as a kid for it. I kind of self-medicated, which led me into a lot of problems with drug addiction and whatnot. Then I finally just had to get sober, and this was many years ago, right around when I married my husband. We're coming up on twelve years of being married. All the doctors were telling me, "It's not going to take just being sober, you're going to have to go on some sort of medication probably." I said, "No I don't, I'm going to be sober and I'm going to get my life together," and I did. I got sober, I still had my weird little head shit, but I was doing pretty good, I'd started working in Europe, things were going pretty good, I was building a career, my second chance career was happening there. I was feeling really good and I was kind of being a little bit of a brat, saying to my doctors, "See, I told you I could get sober," and they were saying , "No, you're in remission. You'd better watch it."
They were right, because about five years ago, I had my worst decline mentally I've ever had, stone cold sober, and ended up going to the hospital. So everything changed. That song was written as soon as I got out, and it was all about what I experienced in there. I'd been to hospitals before, but never for such a long run, and usually when they let you out, you just get semi-stable and then they let you out. But this time, I had to get not only stable but they wanted to keep me and watch, so I was in there for a good month and a week. On the last week that I was there, I realized that whatever kind of darkness in life, all people have their own difficulties they deal with, that we know that when things are really good, we know that they have to change. But I think I forgot that when things are bad that, too, will change. That will also change, and it will get better and it will get hard again and it will get better and it's this journey of life, so I just tried to bring in a lot of different metaphors. In the song, I talk about the outlaw and I talk about the little women dancing and I'm trying to use these different pictures of how when things are good, they get bad, and when they're bad, they get good again, especially at the end of the song when I talk about my mother and my way of saying goodbye to her when she's dying. "Mom, don't be afraid, because it must change. That's part of the natural law. Everything must change."
MR: The title "Everything Must Change" has been used often prior to your own song about life because it's such a constant, it's like street wisdom. People want things to stay as they are, but we just can't.
BH: They cannot. And I think one of the great things to recognize is when things do change for us, especially when they're going good and they get really ugly or really difficult, it's not because we're bad or created something bad, it's just the natural journey of life. Everyone's got their own destiny and their own paths, and I think that our paths are meant to be filled with joy and dreams and even tragedy and that's just a part of it. We can either flow with it or we can pretend like it's not supposed to happen and every time, have our asses kicked because we're expecting it to stay good and that's just not the natural law of things.
MR: And as The Beatles say, we get by with a little help from our friends, for instance, in your case, that would be one of my favorite interviewees, Joe Bonamassa.
BH: Oh God, isn't he a treasure? He's amazing.
MR: Tell me about your relationship with him, because you not only recorded with him, you played together live and became close.
BH: Yeah, we actually just finished another record together last week and we've got a tour coming up in Europe. Joe contacted me first by playing one of my songs on his radio show that he had for a while. He's playing a song, I believe, called "Sick," off of a record of mine called 37 Days. I was doing a small show in London and he came down to the show. I never got a chance to talk to him, but he said to my husband, "I've got an idea, I really want to do a record with Beth that's a cover record of all of our favorite soul songs." I didn't get my hopes up, I know how busy people are in the business. I thought, "Wow, maybe that's the last I'll ever hear of that, so I'll just enjoy that nice gesture. If anything would come of it that would be great, but if it doesn't that's okay too." Some months later, I bumped into him in Holland. We were staying in the same hotel and this was the first time I actually got to see his face. He said, "Dude I really want to do this record," so I said, "Hey, just say when and where." He said, "Make a list of your favorite songs and think of anything that reminds you of soulfulness and I'll do the same and we'll do a record with Kevin Shirley, the guy that I work with." That's exactly what we did. We chose a bunch of different things from Ray Charles to Billie Holiday, Aretha Franklin, Etta James...all kinds of great artists. I had the best time making that record. He's a great guy.
MR: Yeah, he is a great guy. And also you had a little outing with a certain Jeff Beck recently at The Kennedy Center.
BH: Oh, God, yeah, Jeff Beck is my magic man. He's been so amazing to me and my life. I love him so much. I was doing a little TV show in England called Jools Holland... and whenever I'm doing something, he usually comes down. My husband and I have a good relationship with him and his wife. He said, "Just keep your ears open, kid, over these next couple of weeks." I said, "Oh, okay." I got on the road working and I got a call just two weeks later from him. He said, "Hey, I've got this opportunity to represent Buddy Guy on The Kennedy Center honors. Would you like to sing?" I said, "Jeff, with you, I'd do anything, but oh my God, Buddy Guy?" I was so excited about that, and I knew I really wanted to do "Rather Go Blind." It was a song I did on the record with Joe, and Buddy Guy is a huge fan of Etta James who takes credit for writing that song and certainly sang the hell out of it. So I said, "Jeff, what do you think about this song," and I also had to run it by the director of The Kennedy Center Honors, and they thought that it would really be a wonderful thing to do for Buddy since he loves Etta so much. Yeah, man, I got a stylist to give me some clothes so I could look good, because oh my God!
MR: [laughs] Did you wear those clothes on your latest album cover?
BH: Well, I did my album and actually released it already in Europe before I did the Kennedy Center Honors.
MR: I was kidding, sorry.
BH: No, no, no, but it's funny because the same outfit I wore on the frickin' Kennedy Center Honors I just wore on the photo session the other day for Joe, and my latest record we did together last week, we finished and I'm wearing that same outfit. That's pretty funny, what you said is actually true because it's going to be on the front cover of a record.
MR: [laughs] Nice, love it. All right, the question I ask everyone, including you now, oh Beth Hart. What advice do you have for new artists?
BH: Number one, get a great manager who's smart, well-connected, and really, really cares about you personally. It can't just be like you're a meal ticket or he says he's going to make you a star and be all business. Really get someone you can connect with and have an amazing relationship with. Number two, realize that you can't count that fame and money is going to come just because you think you're talented or your mom thinks you're talented. You have to really make a decision and say, "I'm going to do this and I'm going to love this, even if the fame and the money doesn't come, I'm going to dedicate myself to growing as an artist because I love it and it brings me joy and it drives me crazy and all that stuff that life does." It kicks your ass and then it turns you around and gives you a big fat hug and a kiss. And I think you've got to approach it that way because, as we know, there've been so many great artists out there that you've never even heard of, you don't even know they exist, and it doesn't take anything away from their artistry or the relevancy of what they have to say. Sometimes, you've got to get lucky or get promoted properly or timing or whatever. So I would say those two things: Get a great manager, someone you can trust, and make the decision, are you willing to do this, even if fame and money never comes? Because you know, even if fame and money doesn't come, and I'm speaking from serious personal experience here, I have had the time of my life in my career. As a kid, I dreamed of a big house in Malibu, a jet, and the whole world. I didn't get that, but I've had an amazing time. I feel so beyond blessed.
MR: Beth, what advice would you give to the young woman who had a big hit with "LA Song (Out Of This Town)?"
BH: [laughs] My advice to her would be, "It's okay to get lost and f**k up. Forgive yourself, learn how to have compassion, and open up your heart and get back to work and do what you love to do."
MR: So now that you've done your first piano solo on "Swing My Thing Back Around," does that tempt you to do more?
BH: Oh, yeah. You should hear some of the s**t I'm working on today on the piano man, it's just out there. Thelonious Monk would be like, "Hey, bad motherf**ker, keep on working at it!" Even some dark and crazy s**t. I'm having the best time in the world. The best time I've ever had on the piano. The best.
MR: All right, so I don't want to sound sappy but if I wish you really great luck and big success with this record, would you take it well?
BH: Yes, I would actually take it well, thank you! I don't feel the fear like I had before and I think it's partly because I've been around a while. But I think that I'm realizing more now in my life, more than ever, how frickin' lucky I am to be alive, period. So everything else is just cherries on the cake. I can't complain about a thing.
MR: And now that you've mentioned it, what's your favorite cake?
BH: Oh, German chocolate cake. I like wedding cake, too. I love that white, thick, fat frosting that's so sweet you feel like you have a heart attack after one bite. I love so many different kinds of cake. I love pineapple upside-down cake, I could just keep going for years. I love all the cakes. All the cakes.
MR: Is there any random question that I haven't asked you yet?
BH: No, not that I can think of. You've been great.
MR: [laughs] Beth, it's been wonderful and I do appreciate your time. Good luck with everything.
BH: Thank you, thank you so much, and thanks for doing the interview, I really appreciate it.
Tracks:
1. Baddest Blues
2.Bang Bang Boom Boom
3. Better Man
4.Caught Out In The Rain
5. Swing My Thing Back Around
6. With You Everyday
7. Thru The Window Of My Mind
8. Spirit Of God
9. There In Your Heart
10. The Ugliest House On The Block
11. Everything Must Change
Beth Hart Tour Dates:
APRIL
30 Stubbs Indoors, Austin, TX
MAY
2 Hat Tricks, Dallas, TX
4 3rd & Lindsley, Nashville, TN
5 3rd & Lindsley, Nashville, TN
7 Smith's Ole Bar, Atlanta, GA
9 The Birchmere, Alexandria, VA
11 The Blockley, Philadelphia, PA
16 City Winery, New York, NY
17 City Winery, New York, NY
Transcribed by Galen Hawthorne
photo by Wilson Barret
SUZANNE VEGA PRESENTS NOAH CHENFELD ON TOUR
You've got to love it when those who have had success in the biz--especially smart, literate artists like Suzanne Vega--support or mentor young new talent such as Noah Chenfeld. This blooming popster knows how to write a potential hit song better than most superstar acts, and apparently, the audience more than appreciated his recent February 19th, Columbus, Ohio, performance when he opened for the iconic "Luka" and beyond singer-songwriter. Your next op to see this up-and-comer is March 10th at NYC's Rockwood, 196 Allen Street.
Check out Noah's latest recording, "Nothing Now":
photo by Wilson Barret
?
Follow Mike Ragogna on Twitter: www.twitter.com/ragz2008
"; var coords = [-5, -72]; // display fb-bubble FloatingPrompt.embed(this, html, undefined, 'top', {fp_intersects:1, timeout_remove:2000,ignore_arrow: true, width:236, add_xy:coords, class_name: 'clear-overlay'}); });
Source: http://www.huffingtonpost.com/mike-ragogna/embang-bang-boom-boomem-c_b_2738595.html
snow white and the huntsman snow white and the huntsman rupaul drag race walking dead comic kratom broncos broncos
Cure for common hangover? 'Pill' mimics action of human liver in fighting alcohol intoxication
Feb. 20, 2013 ? In a discovery that could promise a quick fix to the common hangover, a team of researchers led by UCLA engineers has identified a method for speeding up the body's reaction to the consumption of alcohol.
In a paper published online Feb. 17 in the peer-reviewed journal Nature Nanotechnology, Yunfeng Lu, a professor of chemical and biomolecular engineering at the UCLA Henry Samueli School of Engineering and Applied Science, and his colleagues describe successfully placing two complementary enzymes in a tiny capsule to speed up the elimination of alcohol from the body. The enzyme combination within the capsule essentially processes alcohol the way the liver does.
Lu, the principal investigator, said the enzyme combination could be ingested as a pill, chemically altering alcohol in the digestive system, even as the liver does its work.
"The pill acts in a way extremely similar to the way your liver does," Lu said. "With further research, this discovery could be used as a preventative measure or antidote for alcohol intoxication."
Naturally occurring enzymes within cells often work in tandem to transform molecules or eliminate toxins. Lu's group assembled multiple enzymes to mimic the natural process. An enzyme known as an alcohol oxidase, for example, can promote the oxidization of alcohol but also produces hydrogen peroxide, which is toxic. Another type of enzyme, a catalase, prompts the decomposition of hydrogen peroxide into water and oxygen. Placing the two enzymes next to each other can effectively remove alcohol.
The researchers placed the two enzymes in a polymer capsule measuring just tens of nanometers in diameter. The wall of the polymer capsule is only one nanometer thick -- about 100,000 times thinner than a strand of human hair. The capsule protects the enzymes and allows them to freely enter an alcohol molecule. In this way, the nanocapsule mimics an organelle, a structure found in cells that spurs chemical reactions.
The researchers used a mouse model to test how well the enzyme package worked as an antidote after alcohol was consumed. They found that blood alcohol levels in mice that received the enzyme package fell more quickly than in mice that did not. Blood alcohol levels of the antidote test group were 15.8 percent lower than the control group after 45 minutes, 26.1 percent lower after 90 minutes and 34.7 percent lower after three hours.
In a test of how well the enzyme delivery system worked as a prophylactic when consumed at the same time as alcohol, the researchers found that blood alcohol levels in the mice that received the enzymes were 10.1 percent lower than in control-group mice after 45 minutes, 31.8 percent lower after 90 minutes and 36.8 percent lower after three hours.
"Considering the vast library of enzymes that are currently or potentially available," the authors write, "novel classes of enzyme nanocomplexes could be built for a broad range of applications."
The study's lead authors included Yang Liu and Juanjuan Du of UCLA Engineering's chemical and biomolecular engineering department.
Additional authors of the research include Wei Wei of UCLA Engineering; Ming Yan of UCLA Engineering and the UCLA Department of Microbiology, Immunology and Molecular Genetics; Mo Yin Lau, Jay Hu, Hui Han and Cheng Ji of the Keck School of Medicine at the University of Southern California; Dr. Otto O. Yang of the David Geffen School of Medicine at UCLA; Sheng Liang and Hui Wang of Xinhua Hospital, affiliated with China's Shanghai Jiao Tong University; Jianmin Li and Wei Chen of China's Beijing Institute of Biotechnology; Xinyuan Zhu of Shanghai Jiao Tong University; and Linqi Shi of China's Ministry of Education and Nankai University.
The research was partially supported by the Defense Threat Reducing Agency, the National Institutes of Health, the National Natural Science Foundation of China, and the National Basic Research Program of China.
Share this story on Facebook, Twitter, and Google:
Other social bookmarking and sharing tools:
Story Source:
The above story is reprinted from materials provided by University of California, Los Angeles. The original article was written by Bill Kisliuk.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
- Yang Liu, Juanjuan Du, Ming Yan, Mo Yin Lau, Jay Hu, Hui Han, Otto O. Yang, Sheng Liang, Wei Wei, Hui Wang, Jianmin Li, Xinyuan Zhu, Linqi Shi, Wei Chen, Cheng Ji, Yunfeng Lu. Biomimetic enzyme nanocomplexes and their use as antidotes and preventive measures for alcohol intoxication. Nature Nanotechnology, 2013; DOI: 10.1038/nnano.2012.264
Note: If no author is given, the source is cited instead.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_science/~3/0ZLTSiBDES0/130220114337.htm
ashley olsen new apple tv sun flare love hewitt new ipad solar flare joseph kony 2012
Thursday, February 21, 2013
S_47P::::10 Things to Know for Today
Please check the URL for proper spelling and capitalization. If you're having trouble locating a destination on Yahoo!, try visiting the Yahoo! homepage or look through a list of Yahoo!'s online services.
Please try Yahoo Help Central if you need more assistance.
Source: http://news.yahoo.com/10-things-know-today-101340019.html
bats hunger games review jeff saturday jason smith jon corzine austin rivers austin rivers
Walker, Northeastern down James Madison 66-64 ? Yahoo! Canada Sports
Via caa "colonial athletic" ? Google News
Walker, Northeastern down James Madison 66-64
Yahoo! Canada Sports
BOSTON (AP) ? Quincy Ford scored 14 points and David Walker made the game-winning jumper to lift Northeastern past James Madison 66-64 Wednesday night in a Colonial Athletic Association contest. Reggie Spencer finished with 13 points and Walker added ?
Click here to read the full article from caa "colonial athletic" ? Google News
http://ifttt.com/images/no_image_card.png
The Feed is a curated aggregation of CAA-related news and blogs. Our goal is to highlight the great articles being written and direct traffic back to the original sources, introducing fans to new places to find news and opinion about the teams and league they follow fervently.
Share with Facebook and Twitter, Email or Print:
- Share
resolute national enquirer whitney houston casket photo jk rowling qnexa kingdom of heaven national enquirer whitney houston arizona republican debate
Wednesday, February 20, 2013
Jill Lawson: Yoga Studios Across America are Embracing FreeFlow: a Unique Path to Freedom of Expression Through Music
[unable to retrieve full-text content]It is certain, that by expressing ourselves through music we will grow, we will heal, we will transform. This is a path to freedom.
Source: http://www.huffingtonpost.com/jill-lawson/the-hang-instrument_b_2680646.html
2012 pro bowl postsecret ufc on fox 2 supercross christina aguilera etta james funeral sundance film festival the flintstones
Genome-wide imaging study identifies new gene associated with Alzheimer's plaques
Feb. 20, 2013 ? A study combining genetic data with brain imaging, designed to identify genes associated with the amyloid plaque deposits found in Alzheimer's disease patients, has not only identified the APOE gene -- long associated with development of Alzheimer's -- but has uncovered an association with a second gene, called BCHE.
A national research team, led by scientists at the Indiana University School of Medicine, reported the results of the study in an article in Molecular Psychiatry posted online February 19. The study is believed to be the first genome-wide association study of plaque deposits using a specialized PET scan tracer that binds to amyloid.
The research also is believed to be the first to implicate variations in the BCHE gene in plaque deposits visualized in living individuals who have been diagnosed with Alzheimer's disease or are at-risk for developing the disease. The enzyme coded by the BCHE gene has previously been studied in post-mortem brain tissue and is known to be found in plaques.
"The findings could recharge research efforts studying the molecular pathways contributing to amyloid deposits in the brain as Alzheimer's disease develops and affects learning and memory," said Vijay K. Ramanan, the paper's first author and an M.D./Ph.D. student at the IU School of Medicine.
The BCHE gene finding "brings together two of the major hypotheses about the development of Alzheimer's disease," said Andrew J. Saykin, Psy.D., Raymond C. Beeler Professor of Radiology and Imaging Sciences at IU and principal investigator for the genetics core of the Alzheimer's Disease Neuroimaging Initiative.
Scientists have long pointed to the loss of an important brain neurotransmitter, acetylcholine, which is depleted early in the development of the disease, as a key aspect of the loss of memory related neurons. The BCHE gene is responsible for an enzyme that breaks down acetylcholine in the brain. The other major Alzheimer's hypothesis holds that the development of the amyloid plaques is the primary cause of the disease's debilitating symptoms. As it turns out, the enzyme for which the BCHE gene codes is also found in significant quantities in those plaques.
"This study is connecting two of the biggest Alzheimer's dots," said Dr. Saykin, director of the Indiana Alzheimer Disease Center and the IU Center for Neuroimaging at the IU Health Neuroscience Center.
"The finding that BCHE gene variant predicts the extent of plaque deposit in PET scans among people at risk for Alzheimer's disease is likely to reinvigorate research into drugs that could modify the disease by affecting the BCHE enzyme or its metabolic pathway," he said. Some existing drugs inhibit this enzyme, but it is unclear whether this influences plaque deposits.
Overall, the results appear to offer scientists new potential targets for drugs to slow, reverse or even prevent the disease. Alzheimer's disease affects an estimated 5.4 million Americans and has proven resistant to treatments that do more than temporarily slow the worsening of symptoms.
Amyloid plaque deposits build up abnormally in the brains of Alzheimer's patients and are believed to play an important role in the memory loss and other problems that plague patients.
The study makes use of an imaging agent, florbetapir, now approved for use by the U.S. Food and Drug Administration, that allows physicians to see the level of plaque buildup in a patient's brain, something that previously could be determined only with an autopsy.
In a genome-wide association study, researchers evaluate alternate versions of many genes to determine whether particular genetic variants are associated with a particular trait -- in this case, the amounts of amyloid plaque deposits that the PET scans revealed in the brains of study participants.
Using the imaging agent that enables detection of the plaques in the brain, the researchers conducted PET scans of 555 participants in the Alzheimer's Disease Neuroimaging Initiative, a long-term public-private research project that includes people at risk for Alzheimer's disease and patients who have been diagnosed with the disease as well as participants with no symptoms.
With sophisticated statistical analyses, the imaging data was combined with analyses of DNA collected from the 555 participants to determine whether particular gene variants were found more often among patients with higher levels of plaque deposits.
The analysis found that a variant in BCHE was significantly associated with the levels of plaque deposits. As would be expected, the analysis also found a strong association with variants of another gene, APOE, that has long been known to be associated with the development of Alzheimer's. The effect of BCHE was independent of APOE, however. Moreover, the effects of the two genes were additive -- that is, people with the suspect variants of both genes had more plaque deposits than people who had only one of the variants associated with plaque development.
Share this story on Facebook, Twitter, and Google:
Other social bookmarking and sharing tools:
Story Source:
The above story is reprinted from materials provided by Indiana University.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
- V K Ramanan, S L Risacher, K Nho, S Kim, S Swaminathan, L Shen, T M Foroud, H Hakonarson, M J Huentelman, P S Aisen, R C Petersen, R C Green, C R Jack, R A Koeppe, W J Jagust, M W Weiner, A J Saykin. APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study. Molecular Psychiatry, 2013; DOI: 10.1038/mp.2013.19
Note: If no author is given, the source is cited instead.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/lcMKpbKxQM4/130220153701.htm
tropic thunder carnie wilson missing reese witherspoon pregnant billy joel bent new york jets
Lawmaker wants to limit contact for football players
NEDERLAND - By Justin Hinton, KFDM News
A state representative has plans to limit the amount of contact during practice for middle and high school football players, all to make the sport safer.
District 38 Representative Eddie Lucio, III introduced the bill to limit full contact football practices to one time per week.
He released a statement saying, ?Texas has been and will continue to be a football state, but we must protect our young athletes. This legislation is aimed at preventing the harm caused by undiagnosed concussions. The cumulative effect of subconcussive hits can lead to severe brain damage because the lack of diagnosis."
Head football coach, Larry Neumann wants to keep kids safe while preserving the integrity of the sport, finding it to be a difficult balance.
?How to legislate it for good reason and apply it in a practical sense is the key, and I don?t think anybody?s got the answer to that yet,? he said.
Representative Lucio?s office told KFDM news he?s in contact with the Texas High School Coach?s Association.
The office said he will not move ahead with the bill until the council is on board, but he will continue pursuing what the staff calls a ?practical and preventative solution? to reducing injuries on the football field.Lawmaker wants to limit contact for football players
walmart best buy sears abercrombie abercrombie Aeropostale Jcpenny
Dominatrix Forklift Ad Ruled Offensive By Advertising... | Stuff.co.nz
An ad for used forklifts featuring a ''sexualised and objectified'' woman in dominatrix-like clothing has earned a South Island company a slap on the wrist from the advertising watchdog.
The ad featured the woman holding a heavy chain, with a forklift in the background. The text read: ''You know you're not the first ... But does that really matter? Used Forklifts.''
The Advertising Standards Authority has upheld a complaint that the ad was offensive, saying the advert used inappropriate sexual appeal.
The Advertising Code states products cannot be promoted through the use of exploitative or degrading sexual images, especially if the product is completely unrelated to such images, as was the case here.
The complainant said it was ''just offensive to see that women's bodies are used to sell a service that clearly targets men''.
''It becomes a sort of attention-seeking behaviour that is in many ways detrimental to how all women are viewed,'' the authority was told.
The advertiser, Independent Forklifts, said the campaign had been running for three years without complaint.
It also stated if the Jockey campaign featuring All Black Dan Carter in his underwear was acceptable, its imagery must be as well.
The Complaints Board said the Jockey ads were different as the product being sold was underwear.
The watchdog also said as the advert was on a vehicle, it would be highly visible to the general public, including children, rather than just its presumed target market of adult men.
If a complaint to the authority is upheld, the advertiser is asked to remove the ad, though there is no punishment.
- ? Fairfax NZ News
Source: http://www.stuff.co.nz/business/industries/8322044/Saucy-forklift-ad-deemed-offensive
joba chamberlain new york mega millions jetblue jetblue michelle malkin october baby sugarland
Tuesday, February 19, 2013
Former NC State coach Lowe arrested on tax charges
RALEIGH, N.C. (AP) ? Former North Carolina State basketball coach Sidney Lowe was arrested Monday and charged with failing to file his North Carolina state income taxes for three years.
Lowe, currently an assistant with the NBA's Utah Jazz, didn't file returns in 2009, 2010 and 2011 ? the last three years he coached the Wolfpack, according to the state Department of Revenue. He was booked at the Wake County jail Monday and released on a $10,000 unsecured bond on the misdemeanor charges.
Lowe was not with the Jazz when they returned to practice Monday night after the All-Star break, but head coach Tyrone Corbin said Lowe would be with the team Tuesday when it faces Golden State in Salt Lake City.
"It's a personal matter," said Corbin, who indicated he had spoken with Lowe. "We'll deal with it. He'll make a statement at some point, but it's a personal matter."
Corbin said he doesn't believe Lowe's arrest will affect the team as it gears up for a stretch run toward the playoffs.
Jazz center Al Jefferson, who has had to deal with off-court issues in the past, also said it wouldn't affect the team.
"Coach is a great guy," Jefferson said. "I don't know the story. ... he'll take care of. "
At N.C. State, Lowe was paid a base salary of around $210,000 per year. That was boosted to $760,000 with television and radio commitments, and with bonuses and endorsements could have been up to $900,000 a year. A contract settlement after his 2011 resignation was expected to pay Lowe around $900,000, athletic director Debbie Yow said then.
Jazz general manager Dennis Lindsey declined comment about Lowe's arrest.
Lowe couldn't be reached for comment, and it wasn't known if he had an attorney.
Lowe kept his home in Wake Forest, north of Raleigh, even after taking the job with the Jazz, authorities said. He ignored a television reporter's request for comment Monday as he walked out of the home and entered an airport taxi.
Lowe was one of the most beloved players in N.C. State history for his role as starting point guard on the "Cardiac Pack" team that won the 1983 NCAA championship. He returned to Raleigh in 2006 to replace Herb Sendek as coach, but the Wolfpack struggled to sustain any momentum in Lowe's five seasons. He never made the NCAA tournament as a coach.
The Wolfpack never finished higher than ninth in the Atlantic Coast Conference under Lowe. He went 86-78, including just 25-55 in ACC play. Lowe was 3-16 record against rivals Duke and North Carolina, with two of those wins coming in his first year.
Lowe twice reached the NIT. He resigned in 2011 and the school hired Mark Gottfried, the current coach.
Lowe also spent five years as an NBA head coach in Minnesota and Memphis, compiling a 79-228 record.
___
Sports Writer Lynn DeBruin in Salt Lake City contributed to this report.
Associated PressJavon Belcher express kindle fire Jenny Johnson olivier martinez ny lottery Ohio Lottery
How Google Makes Android Understand You
Source: http://feeds.gawker.com/~r/gizmodo/full/~3/6COhPQk_h60/how-google-makes-android-understand-you
buckeye west side story final four 2012 bridesmaids winning lottery numbers megamillions winner kansas jayhawks
Intel Israel more than doubles exports, mulls new investment
Intel?s Israeli subsidiary more than doubled its exports in 2012 to $4.6 billion and is seeking to bring manufacturing of the company?s next generation of chips to Israel.
Intel?s exports, which rose 109 percent from $2.2 billion in 2011, were boosted by the start of production of chips using 22 nanometer technology at its Kiryat Gat plant in southern Israel, which is now operating at full capacity.
Intel, the world?s No. 1 chipmaker, will build chips over the next two to three years with features measuring just 14 nm in Ireland and the United States but the company is already thinking about where it will produce 10 nm chips. The narrower the features, the more transistors can fit on a single chip, improving performance.
Intel Israel executives said they would like to see 10 nm production in Israel.
?The average life of a technology is two to six years so we need to be busy to get the next technology, 10 nanometer,? Maxine Fassberg, general manager of Intel Israel, told a news conference on Sunday. ?We need to get a decision far enough in advance to be able to upgrade the plant. So for 10 nanometer, decisions will need to be made this year.?
Fassberg said upgrading the existing Fab 28 plant in Israel would require a lower investment than building a new plant but would still involve several billion dollars.
Intel Israel has in the past received government grants to help with the costs of its investments and Fassberg told Reuters the company was ?constantly in talks with the government?.
Intel has invested $10.5 billion in Israel in the past decade, including $1.1 billion in 2012, and has received $1.3 billion in government grants.
The company accounted for 20 percent of Israel?s high-tech exports last year and 10 percent of its industrial exports, excluding diamonds.
?If Intel had not increased its exports, Israel?s high-tech exports would have shrunk by 10 percent,? Intel Israel President Mooly Eden said.
Most of Intel Israel?s exports - $3.5 billion - came from its chip manufacturing activities.
Intel is Israel?s largest private employer, with 8,542 workers, up 10 percent from 2011. The company has two plants - in Jerusalem and Kiryat Gat - as well as four research and development centers.
Eden said Intel was also committed to investing in start-ups, having invested in 64 Israeli companies since 1996. In July its global investment arm Intel Capital said it would expand its operations in Israel.
Source: http://feedproxy.google.com/~r/cxotoday/~3/t9_mOTqH1vw/
Sherman Hemsley Olympics Opening Ceremony Katherine Jackson Olympics Opening Ceremony Time paris jackson paris jackson US weekly
WH Chief of Staff on Leaked Immigration Proposal: Let's Make Sure It Doesn't Have to be Proposed
In Beyonc?'s new documentary about Beyonc? co-directed by Beyonc? there's a shot of her flying in a helicopter checking her iPhone. As we see the real world below, the world of people who don't get to take those luxurious rides, Beyonc? says the following, in Beyonc? voiceover: "I think people have an idea in their heads about entertainers, celebrities. I think they feel like their lives are so perfect, and it's really hard to go through painful experiences when you're in the public eye, because it's hard to have closure. ...
bachelor pad Green Coffee Bean Extract september 11 9/11 Memorial 911 masterchef Dictionary.com
Sunday, February 17, 2013
Payroll Tax Hike And Auto Sales - Business Insider
Retail sales climbed by just 0.1 percent in January.? While this number may seem week, it was right in line with expectations.? And it was seen as confirmation that the initial impact of the recent payroll tax hike wasn't any worse than expected.
Most economists argue that we'll have to wait a month or two before we really understand the full impact of the tax hike.? (Indeed, leaked emails from Walmart suggest the impact of the tax hike is much worse than we think.)
However, Deutsche Bank's Joseph LaVorgna and Carl Riccadonna are particularly encouraged by one component of the recent retail sales report: auto sales.
From DB:
Additionally, January light unit motor vehicle sales totaled 15.3 million at an annual rate, the third-fastest pace since the last recession and barely down from December?s 15.4 million annualized tally. Thus far, consumers are not retrenching to the degree that many analysts feared. As a result, January retail sales are easily consistent with our expectation that personal consumption will rise at least 1.0% in the quarter, although the risks appear to be tilting toward a stronger number...
Deutsche Bank |
Still, LaVorgna and Riccadonna will wait for the January income and spending report before they get really excited.
...the January personal income and spending report, which is released March 1, will provide significant additional information with respect to households? behavioral response to higher tax rates. In that report we will be watching in particular to see the overall trend in income growth (i.e. the dispersion between December and January due to tax optimization?this applies to both dividend and wage income), as well as the degree to which households may be dipping into savings (i.e. a lower savings rate) to support current quarter consumption.
If households, confident in improving job and income prospects, decide to temporarily push their savings rate lower?the economy could avoid the hit from the payroll tax hike...
Source: http://www.businessinsider.com/payroll-tax-hike-and-auto-sales-2013-2
alcatraz martin luther king jr. zappos john elway john elway i have a dream speech fox news debate
The Guardian - Mass wedding in South Korea ? in pictures - World news - guardian.co.uk
3,500 couples from countries all around the world exchanged wedding vows in a mass wedding ceremony at Cheongshim Peace World Centre in Gapyeong-gun today. The blessing is a regular event in the Unification Church's calender, and has been taking place since the early sixties. It's the first mass wedding since the death of the church's founder, Moon Sun-Myung, in September last year. The service is now run by his widow, Hak Ja Han Moon
the monkees ciaa love actually strikeforce davy jones deep impact miesha tate vs ronda rousey
Rihanna brings pop star casual in London catwalk debut, follows Issa, others
LONDON - No one went to Rihanna's Saturday night debut as a fashion designer expecting demure dresses set off with tasteful pearls.
So no one was surprised by the double-volume hip-hop music, smoke machines and champagne that greeted guests at the unveiling of her Rihanna for River Island collection.
And few were taken aback by the bad girl, rock chick styling of some of her clothes, with tight-fitting jersey outfits and dresses cut to show more than a bit of leg.
It was a fun, flattering collection aimed at young women, containing nothing shocking or outrageous from a singer who has been known to bring those elements to her live performances.
Many of the outfits had a simple, monochrome look ? in off-reds, yellow, navy, black and other colours ? and they were cut to look good on those blessed with a fit physique.
Some were satin, some jersey, and some of the short skirts were made with denim and matched with crop tops or T-shirts.
Rihanna also tried her hand at a few elegant, semi-sheer dresses that were predominantly black with white floral patterns.
Some models wore shirts tied around their waists, Rihanna-style.
The singer appeared unusually shy but happy in her brief appearance on the catwalk to take in the audience's applause. She wore a short black dress as she waved to her fans.
The collection will be sold at River Island stores throughout the world.
luke kuechly brad miller chandler jones peyton hillis fletcher cox charlotte bobcats new york rangers
Saturday, February 16, 2013
REFILE-UPDATE 1-Cricket-South Africa v Pakistan second test scoreboard
(Inserts dropped bowler's name in South African innings) CAPE TOWN, Feb 16 (Reuters) - Scoreboard on the third day of the second test between South Africa and Pakistan at Newlands on Saturday. Pakistan first innings 338 (Younus Khan 111, Asad Shafiq 111; V.Philander 5/59) South Africa first innings (139 for five overnight) G. Smith lbw Ajmal 19 A. Petersen c Azhar Ali b Ajmal 17 H. Amla lbw b Ajmal 25 F. du Plessis c Younus Khan b Ajmal 28 J. Kallis lbw b Ajmal 2 AB de Villiers c Gul b Irfan 61 D. Elgar c Younus Khan b Ajmal 23 R. Peterson c Gul b Hafeez 84 V. Philander c Jamshed b Irfan 22 D. Steyn c Sarfraz b Irfan 10 M. Morkel not out 8 Extras (b-12 lb-8 nb-7) 27 Total (all out, 102.1 overs) 326 Fall of wickets: 1-36 2-50 3-84 4-102 5-109, 6-164, 7-210, 8-277, 9-303, 10-326. Bowling: Umar Gul 20-5-74-0, Tanvir Ahmed 10-4-26-0 (2nb), Mohammad Irfan 21-1-86-3 (5nb), Saeed Ajmal 42-9-96-6, Mohammad Hafeez 9.1-1-24-1. Pakistan second innings Mohammad Hafeez lbw Steyn 0 Nasir Jamshed lbw Philander 0 Azhar Ali not out 45 Younus Khan b Steyn 14 Misbah-ul-Haq not out 36 Extras (lb-2 w-3) 5 Total (for three wickets, 44 overs) 100 Fall of wickets: 1-0 2-7 3-45. Bowling: Steyn 9-2-24-2, Philander 11-4-26-1, Morkel 3.1-0-8-0, Peterson 15-5-32-0, Kallis 5.5-2-8-0. South Africa won the toss and elected to field. (Compiled by Nick Said, editing by John Mehaffey)
amanda bynes dui ghost ship tiger woods masters jet crash virginia beach petrino clayton kershaw tyler perry
Nancy Pelosi: Congressional pay cut would diminish the dignity of lawmakers? jobs (Michellemalkin)
Subscribe to:
Posts (Atom)